Papers in scientific journals


Barbosa, D.J., Capela, J.P., Ferreira, L.M. et al. Ecstasy metabolites and monoamine neurotransmitters upshift the Na+/K+ ATPase activity in mouse brain synaptosomes. Arch Toxicol 96, 3279–3290 (2022).

Bego T, Meseldžić N, Prnjavorac B, Prnjavorac L, Marjanović D, Azevedo R, Pinto E, Duro M, Couto C, Almeida A. Association of trace element status in COVID-19 patients with disease severity. J Trace Elem Med Biol. 2022 Dec;74:127055. doi: 10.1016/j.jtemb.2022.127055.

Vieira, S.F.; Gonçalves, V.M.F.; Llaguno, C.P.; Macías, F.; Tiritan, M.E.; Reis, R.L.; Ferreira, H.; Neves, N.M. On the Bioactivity of Echinacea purpurea Extracts to Modulate the Production of Inflammatory Mediators. Int. J. Mol. Sci. 2022, 23, 13616.

Coimbra, S.; Rocha, S.; Valente, M.J.; Catarino, C.; Bronze-da-Rocha, E.; Belo, L.; Santos-Silva, A. New Insights into Adiponectin and Leptin Roles in Chronic Kidney Disease. Biomedicines 2022, 10, 2642.

Rodrigues, S.B.; de Faria, L.P.; Monteiro, A.M.; Lima, J.L.; Barbosa, T.M.; Duarte, J.A. EMG Signal Processing for the Study of Localized Muscle Fatigue—Pilot Study to Explore the Applicability of a Novel Method. Int. J. Environ. Res. Public Health 2022, 19, 13270.

Barroso, T.G.; Ribeiro, L.; Gregório, H.; Monteiro-Silva, F.; Neves dos Santos, F.; Martins, R.C. Point-of-Care Using Vis-NIR Spectroscopy for White Blood Cell Count Analysis. Chemosensors 2022, 10, 460.

Oliveira, N.G.; Dinis-Oliveira, R.J. Genotoxic Aspects of Psychoactive Substances. Psychoactives 2022, 1, 64-69.

Rebelo A, Duarte B, Ferreira C, Mourão J, Ribeiro S, Freitas AR, Coque TM, Willems R, Corander J, Peixe L, Antunes P, Novais C. Enterococcus spp. from chicken meat collected 20 years apart overcome multiple stresses occurring in the poultry production chain: Antibiotics, copper and acids. Int J Food Microbiol. 2023 Jan 2;384:109981. doi: 10.1016/j.ijfoodmicro.2022.109981.

Novais C, Almeida-Santos AC, Paula Pereira A, Rebelo A, Freitas AR, Peixe L. Alert for molecular data interpretation when using Enterococcus faecium reference strains reclassified as Enterococcus lactis. Gene. 2022 Oct 17;851:146951. doi: 10.1016/j.gene.2022.146951

Carvalho, I.P.; Peixoto, B.; Caldas, J.C.; Costa, A.; Silva, S.; Moreira, B.; Almeida, A.; Moreira-Rosário, A.; Guerra, A.; Delerue-Matos, C.; Sintra, D.; Pestana, D.; Pinto, E.; Mendes, F.C.; Martins, I.; Leite, J.C.; Fontoura, M.; Maia, M.L.; Queirós, P.; Moreira, R.; Leal, S.; Norberto, S.; Costa, V.; Fernandes, V.C.; Keating, E.; Azevedo, L.; Calhau, C. Association between Elevated Iodine Intake and IQ among School Children in Portugal. Nutrients 2022, 14, 4493.

Nogueira, S.; Barbosa, J.; Faria, J.; Sá, S.I.; Cardoso, A.; Soares, R.; Fonseca, B.M.; Leal, S. Unhealthy Diets Induce Distinct and Regional Effects on Intestinal Inflammatory Signalling Pathways and Long-Lasting Metabolic Dysfunction in Rats. Int. J. Mol. Sci. 2022, 23, 10984.

Ribeiro, C., Almeida, A., & Couto, C. . (2022). The Aquatic macrophytes as bioindicators of heavy metals contamination in estuarine ecosystems. Scientific Letters, 1(1), 5.

Dinis-Oliveira, R.J.; Magalhães, T. Driving under the Influence of Psychotropic Substances: A Technical Interpretation. Psychoactives 2022, 1, 7-15.

Nunes, M.; Duarte, D.; Vale, N.; Ricardo, S. Pitavastatin and Ivermectin Enhance the Efficacy of Paclitaxel in Chemoresistant High-Grade Serous Carcinoma. Cancers 2022, 14, 4357.

Pereira AP, Antunes P, Willems R, Corander J, Coque TM, Peixe L, Freitas AR, Novais C. Evolution of Chlorhexidine Susceptibility and of the EfrEF Operon among Enterococcus faecalis from Diverse Environments, Clones, and Time Spans. Microbiol Spectr. 2022 Jul 7:e0117622. doi: 10.1128/spectrum.01176-22.

Freitas AR, Werner G. Antibiotic susceptibility testing for therapy and antimicrobial resistance surveillance: genotype beats phenotype? Future Microbiol. 2022 Jul 14. doi: 10.2217/fmb-2022-0109. 

Ribeiro, C., Almeida, A., & Couto, C. . (2022). The Aquatic macrophytes as bioindicators of heavy metals contamination in estuarine ecosystems. Scientific Letters, 1(1), 5.

Vieira-Pinto P, Muñoz-Barús JI, Taveira-Gomes T, Vidal-Alves MJ, Magalhães T. Prosecutorial decision-making regarding offenders' social reintegration programs in intimate partner violence cases. A Portuguese study. PLoS One. 2022 Jun 16;17(6):e0269820. doi: 10.1371/journal.pone.0269820.

Valente-Aguiar MS, de Carvalho ER, Magalhães T, Dinis-Oliveira RJ. Fatal iatrogenic cardiac tamponade due to central venous catheterization. Forensic Sci Med Pathol. 2022 Jun 13. doi: 10.1007/s12024-022-00491-4. 

Silva, P.M.A.; Bousbaa, H. BUB3, beyond the Simple Role of Partner. Pharmaceutics 2022, 14, 1084.

Ricardo S, Canão P, Martins D, Magalhães AC, Pereira M, Ribeiro-Junior U, de Mello ES, Alves VA, Pinto R, Leitão D, Alves G, Oliveira R, Wilton J, Costelha S, Meireles D, Cabanes D, David L, Schmitt F. Searching for SARS-CoV-2 in Cancer Tissues: Results of an Extensive Methodologic Approach based on ACE2 and Furin Expression. Cancers (Basel). 2022 May 24;14(11):2582. doi: 10.3390/cancers14112582. 

Pinto JO, Dores AR, Peixoto B, Vieira de Melo BB, Barbosa F. Critical review of multisensory integration programs and proposal of a theoretical framework for its combination with neurocognitive training. Expert Rev Neurother. 2022 Jun 27:1-10. doi: 10.1080/14737175.2022.2092401.

Pinto, B.; Novais, P.; Henriques, A.C.; Carvalho-Tavares, J.; Silva, P.M.A.; Bousbaa, H. Navitoclax Enhances the Therapeutic Effects of PLK1 Targeting on Lung Cancer Cells in 2D and 3D Culture Systems. Pharmaceutics 2022, 14, 1209.

Moreira S, Criado MB, Ferreira MS, Machado J, Gonçalves C, Mesquita C, Lopes S, Santos PC. The Effects of COVID-19 Lockdown on the Perception of Physical Activity and on the Perception of Musculoskeletal Symptoms in Computer Workers: Comparative Longitudinal Study Design. Int J Environ Res Public Health. 2022 Jun 14;19(12):7311. doi: 10.3390/ijerph19127311. 

Kumar, H.; Bhardwaj, K.; Cruz-Martins, N.; Sharma, R.; Siddiqui, S.A.; Dhanjal, D.S.; Singh, R.; Chopra, C.; Dantas, A.; Verma, R.; Dosoky, N.S.; Kumar, D. Phyto-Enrichment of Yogurt to Control Hypercholesterolemia: A Functional Approach. Molecules 2022, 27, 3479.

Jamloki, A.; Trivedi, V.L.; Nautiyal, M.C.; Semwal, P.; Cruz-Martins, N. Poisonous Plants of the Indian Himalaya: An Overview. Metabolites 2022, 12, 540.

Garcia J, Carvalho A, das Neves RP, Malheiro R, Rodrigues DF, Figueiredo PR, Bovolini A, Duarte JA, Costa VM, Carvalho F. Antidotal effect of cyclosporine A against α-amanitin toxicity in CD-1 mice, at clinical relevant doses. Food Chem Toxicol. 2022 Jun 6;166:113198. doi: 10.1016/j.fct.2022.113198.

Barbosa, J.C.; Almeida, D.; Machado, D.; Sousa, S.; Freitas, A.C.; Andrade, J.C.; Gomes, A.M. Spray-Drying Encapsulation of the Live Biotherapeutic Candidate Akkermansia muciniphila DSM 22959 to Survive Aerobic Storage. Pharmaceuticals 2022, 15, 628.

Vedovello, P., Costa, J. A. S., Fernandes, C., Tiritan, M. E., & Paranhos, C. M. (2022). Evaluation of chiral separation by Pirkle-type chiral selector based mixed matrix membranes. Separation and Purification Technology, 289. doi:10.1016/j.seppur.2022.120722

Sharifi-Rad, J., Quispe, C., Durazzo, A., Lucarini, M., Souto, E. B., Santini, A., . . . Cruz-Martins, N. (2022). Resveratrol’ biotechnological applications: Enlightening its antimicrobial and antioxidant properties. Journal of Herbal Medicine, 32. doi:10.1016/j.hermed.2022.100550

Roque Bravo R, Faria AC, Brito-da-Costa AM, Carmo H, Mladěnka P, Dias da Silva D, Remião F, On Behalf Of The Oemonom Researchers. Cocaine: An Updated Overview on Chemistry, Detection, Biokinetics, and Pharmacotoxicological Aspects including Abuse Pattern. Toxins (Basel). 2022 Apr 13;14(4):278. doi: 10.3390/toxins14040278.

Nunes M, Silva PMA, Coelho R, Pinto C, Resende A, Bousbaa H, Almeida GM, Ricardo S. Corrigendum: Generation of Two Paclitaxel-Resistant High-Grade Serous Carcinoma Cell Lines With Increased Expression of P-Glycoprotein. Front Oncol. 2022 Feb 4;12:853608. doi: 10.3389/fonc.2022.853608. 

Martins A, da Silva DD, Silva R, Carvalho F, Guilhermino L. Long-term effects of lithium and lithium-microplastic mixtures on the model species Daphnia magna: Toxicological interactions and implications to 'One Health'. Sci Total Environ. 2022 Sep 10;838(Pt 1):155934. doi: 10.1016/j.scitotenv.2022.155934.

Kumar, H., Bhardwaj, K., Kuča, K., Sharifi-Rad, J., Verma, R., Machado, M., Dinesh, K., Cruz-Martins, N. (2022). Edible mushrooms’ enrichment in food and feed: A mini review. International Journal of Food Science and Technology, 57(3), 1386-1398. doi:10.1111/ijfs.15546

Karić, N., Maia, A. S., Teodorović, A., Atanasova, N., Langergraber, G., Crini, G., . . . Đolić, M. (2022). Bio-waste valorisation: Agricultural wastes as biosorbents for removal of (in)organic pollutants in wastewater treatment. Chemical Engineering Journal Advances, 9. doi:10.1016/j.ceja.2021.100239

Janoušek J, Pilařová V, Macáková K, Nomura A, Veiga-Matos J, Silva DDD, Remião F, Saso L, Malá-Ládová K, Malý J, Nováková L, Mladěnka P. Vitamin D: sources, physiological role, biokinetics, deficiency, therapeutic use, toxicity, and overview of analytical methods for detection of vitamin D and its metabolites. Crit Rev Clin Lab Sci. 2022 May 16:1-38. doi: 10.1080/10408363.2022.2070595.

Gonçalves L, Cravo S, Fernandes C, Tiritan ME. Development and evaluation of Pirkle-type chiral stationary phase for flash chromatography. J Chromatogr A. 2022 Jul 19;1675:463156. doi: 10.1016/j.chroma.2022.463156. 

Dinis-Oliveira RJ. Open-access Mega-journals in Health and Life Sciences: What Every Researcher needs to know about this Publishing Model. Curr Drug Res Rev. 2022;14(1):3-5. doi: 10.2174/2589977514666220209101713.

Černáková, L.; Líšková, A.; Lengyelová, L.; Rodrigues, C.F. Prevalence and Antifungal Susceptibility Profile of Oral Candida spp. Isolates from a Hospital in Slovakia. Medicina 2022, 58, 576.

Magalhães, T.; Dinis-Oliveira, R.J.; Taveira-Gomes, T. Digital Health and Big Data Analytics: Implications of Real-World Evidence for Clinicians and Policymakers. Int. J. Environ. Res. Public Health 2022, 19, 8364.

Lopes-Rocha L, Hernandez C, Gonçalves V, Pinho T, Tiritan ME. Analytical Methods for Determination of BPA Released from Dental Resin Composites and Related Materials: A Systematic Review. Crit Rev Anal Chem. 2022 Jul 1:1-16. doi: 10.1080/10408347.2022.2093097. 

Couto C, Pinto E, Almeida A. Trace Elements as Contaminants and Nutrients. Foods. 2022 May 4;11(9):1337. doi: 10.3390/foods11091337.

Couto CMCM, Ribeiro C. Pollution status and risk assessment of trace elements in Portuguese water, soils, sediments, and associated biota: a trend analysis from the 80s to 2021. Environ Sci Pollut Res Int. 2022 May 14. doi: 10.1007/s11356-022-20699-9.

Dinis-Oliveira, R.J.; Madureira-Carvalho, Á.; Fernandes, L.; Caldas, I.M.; Azevedo, R.M.S. The Portuguese Association of Forensic Sciences Model for Forensic Expert Certification: An Urgent Need and Regulation Proposal. Forensic Sci. 20222, 417-422.

Gavina, C.; Carvalho, D.S.; Valente, F.; Bernardo, F.; Dinis-Oliveira, R.J.; Santos-Araújo, C.; Taveira-Gomes, T. 20 Years of Real-World Data to Estimate the Prevalence of Heart Failure and Its Subtypes in an Unselected Population of Integrated Care Units. J. Cardiovasc. Dev. Dis. 20229, 149.

Dinis-Oliveira RJ (2022). One image is worth more than a thousand words: producing an atlas of medical signs for teaching clinical and forensic toxicology. Forensic Sciences Research, DOI: 10.1080/20961790.2022.2059837

Machado D, Barbosa JC, Domingos M, Almeida D, Andrade JC, Freitas AC, Gomes AM. Revealing antimicrobial resistance profile of the novel probiotic candidate Faecalibacterium prausnitzii DSM 17677. Int J Food Microbiol. 2022 Feb 16;363:109501. doi: 10.1016/j.ijfoodmicro.2021.109501.

Taheri Y, Quispe C, Herrera-Bravo J, Sharifi-Rad J, Ezzat SM, Merghany RM, Shaheen S, Azmi L, Prakash Mishra A, Sener B, Kılıç M, Sen S, Acharya K, Nasiri A, Cruz-Martins N, Tsouh Fokou PV, Ydyrys A, Bassygarayev Z, Daştan SD, Alshehri MM, Calina D, Cho WC. Urtica dioica-Derived Phytochemicals for Pharmacological and Therapeutic Applications. Evid Based Complement Alternat Med. 2022 Feb 24;2022:4024331. doi: 10.1155/2022/4024331. 

Silva B, Soares J, Rocha-Pereira C, Mladěnka P, Remião F, On Behalf Of The Oemonom Researchers. Khat, a Cultural Chewing Drug: A Toxicokinetic and Toxicodynamic Summary. Toxins (Basel). 2022 Jan 20;14(2):71. doi: 10.3390/toxins14020071. 

Pinto, B., Pacheco, C., Silva, P., Carvalho-Tavares , J., Sarmento, B., & Bousbaa, H. (2022). Nanomedicine internalization and penetration: why should we use spheroids?. Scientific Letters, 1(1), 3.

Olival A, Vieira SF, Gonçalves VMF, Cunha C, Tiritan ME, Carvalho A, Reis RL, Ferreira H, Neves NM. Erythrocyte-derived liposomes for the treatment of inflammatory diseases. J Drug Target. 2022 Apr 25:1-11. doi: 10.1080/1061186X.2022.2066107.

Nunes M, Pacheco F, Coelho R, Leitão D, Ricardo S, David L. Mesothelin Expression Is Not Associated with the Presence of Cancer Stem Cell Markers SOX2 and ALDH1 in Ovarian Cancer. Int J Mol Sci. 2022 Jan 18;23(3):1016. doi: 10.3390/ijms23031016

Nogueira S, Garcez F, Sá S, Moutinho LC, Cardoso A, Soares R, Fonseca BM, Leal S. Early unhealthy eating habits underlie morpho-functional changes in the liver and adipose tissue in male rats. Histochem Cell Biol. 2022 Jun;157(6):657-669. doi: 10.1007/s00418-022-02092-2.

Moreira S, Criado MB, Ferreira MS, Machado J, Gonçalves C, Clemente FM, Mesquita C, Lopes S, Santos PC. Positive Effects of an Online Workplace Exercise Intervention during the COVID-19 Pandemic on Quality of Life Perception in Computer Workers: A Quasi-Experimental Study Design. Int J Environ Res Public Health. 2022 Mar 7;19(5):3142. doi: 10.3390/ijerph19053142.

Magalhães AC, Ricardo S, Moreira AC, Nunes M, Tavares M, Pinto RJ, Gomes MS, Pereira L. InfectionCMA: A Cell MicroArray Approach for Efficient Biomarker Screening in In Vitro Infection Assays. Pathogens. 2022 Mar 3;11(3):313. doi: 10.3390/pathogens11030313.

Hossain R, Quispe C, Herrera-Bravo J, Beltrán JF, Islam MT, Shaheen S, Cruz-Martins N, Martorell M, Kumar M, Sharifi-Rad J, Ozdemir FA, Setzer WN, Alshehri MM, Calina D, Cho WC. Neurobiological Promises of the Bitter Diterpene Lactone Andrographolide. Oxid Med Cell Longev. 2022 Feb 1;2022:3079577. doi: 10.1155/2022/3079577. 

Gimondi S, Guimarães CF, Vieira SF, Gonçalves VMF, Tiritan ME, Reis RL, Ferreira H, Neves NM. Microfluidic mixing system for precise PLGA-PEG nanoparticles size control. Nanomedicine. 2022 Feb;40:102482. doi: 10.1016/j.nano.2021.102482. 

Gavina C, Carvalho DS, Dias DM, Bernardo F, Martinho H, Couceiro J, Santos-Araújo C, Dinis-Oliveira RJ, Taveira-Gomes T. Premature Mortality in Type 2 Diabetes Mellitus Associated with Heart Failure and Chronic Kidney Disease: 20 Years of Real-World Data. J Clin Med. 2022 Apr 11;11(8):2131. doi: 10.3390/jcm11082131. 

Freitas, A.R.; Tedim, A.P.; Almeida-Santos, A.C.; Duarte, B.; Elghaieb, H.; Abbassi, M.S.; Hassen, A.; Novais, C.; Peixe, L. High-Resolution Genotyping Unveils Identical Ampicillin-Resistant Enterococcus faecium Strains in Different Sources and Countries: A One Health Approach. Microorganisms 2022, 10, 632.

Couto, C.; Almeida, A. Metallic Nanoparticles in the Food Sector: A Mini-Review. Foods 202211, 402.

Abedini, F.; Mohammadi, S.R.; Dahmardehei, M.; Ajami, M.; Salimi, M.; Khalandi, H.; Mohsenzadegan, M.; Seif, F.; Shirvan, B.N.; Yaalimadad, S.; Roudbary, M.; Rodrigues, C.F. Enhancing of Wound Healing in Burn Patients through Candida albicans β-Glucan. J. Fungi 20228, 263.

Teixeira A, Ribeiro C, Gaio R, Torres T, Magina S, Pereira T, Teixeira M, Rocha JC, Lobo JMS, Almeida IF, Vidal DG, Pedrosa E Sousa HF, Dinis MAP, Almeida V. Influence of psoriasis lesions' location and severity on psychosocial disability and psychopathology. Observational study and psychometric validation of the SAPASI Portuguese version. J Psychosom Res. 2022 Mar;154:110714. doi: 10.1016/j.jpsychores.2021.110714.

Sharifi-Rad J, Quispe C, Kumar M, Akram M, Amin M, Iqbal M, Koirala N, Sytar O, Kregiel D, Nicola S, Ertani A, Victoriano M, Khosravi-Dehaghi N, Martorell M, Alshehri MM, Butnariu M, Pentea M, Rotariu LS, Calina D, Cruz-Martins N, Cho WC. Hyssopus Essential Oil: An Update of Its Phytochemistry, Biological Activities, and Safety Profile. Oxid Med Cell Longev. 2022 Jan 13;2022:8442734. doi: 10.1155/2022/8442734.

Martins RC, Barroso TG, Jorge P, Cunha M, Santos F. Unscrambling spectral interference and matrix effects in Vitis vinifera Vis-NIR spectroscopy: Towards analytical grade ‘in vivo’ sugars and acids quantification. Computers and Electronics in Agriculture Volume 194, March 2022, 106710.

Reis Sousa N, Rocha S, Santos-Silva A, Coimbra S, Valente MJ. Cellular and Molecular Pathways Underlying the Nephrotoxicity of Gadolinium. Toxicol Sci. 2022 Feb 28;186(1):134-148. doi: 10.1093/toxsci/kfab148.

Moreira-Pais A, Ferreira R, Oliveira PA, Duarte JA. A neuromuscular perspective of sarcopenia pathogenesis: deciphering the signaling pathways involved. Geroscience. 2022 Jun;44(3):1199-1213. doi: 10.1007/s11357-021-00510-2. Epub 2022 Jan 4. 

Azevedo C, Casal G, Soares EC, Oliveira E, Rocha S, Hine M, Silva TJ. Hemagglutination in gill capillaries of sheepshead, Archosargus probatocephalus (Perciformes: Sparidae), infected by a myxosporidean. Rev Bras Parasitol Vet. 2022 Jan 14;31(1):e018121. doi: 10.1590/S1984-29612022001.

Carvalho AR, Pérez-Pereira AI, Couto CMC, Tiritan ME, Ribeiro CMR. Assessment of effluents quality through ecotoxicological assays: evaluation of three wastewater treatment plants with different technologies. Environ Sci Pollut Res Int. 2021 Aug 3.


Monteiro L, Silva P, Delgado L, Amaral B, Garcês F, Salazar F, Pacheco JJ, Lopes C, Bousbaa H, Warnakulasuriya S. Expression of spindle assembly checkpoint proteins BubR1 and Mad2 expression as potential biomarkers of malignant transformation of oral leukoplakia: an observational cohort study. Med Oral Patol Oral Cir Bucal. 2021 Nov 1;26(6):e719-e728. doi: 10.4317/medoral.24511.

Sharifi-Rad, J., Quispe, C., Ayatollahi, S. A., Kobarfard, F., Staniak, M., Stȩpień, A., . . . Cho, W. C. (2021). Chemical Composition, Biological Activity, and Health-Promoting Effects of Withania somnifera for Pharma-Food Industry Applications. Journal of Food Quality, 2021. doi:10.1155/2021/8985179

Reis-Mendes A, Padrão AI, Duarte JA, Gonçalves-Monteiro S, Duarte-Araújo M, Remião F, Carvalho F, Sousa E, Bastos ML, Costa VM. Role of Inflammation and Redox Status on Doxorubicin-Induced Cardiotoxicity in Infant and Adult CD-1 Male Mice. Biomolecules. 2021 Nov 19;11(11):1725. doi: 10.3390/biom11111725. 

Dias da Silva, D., Silva, J. P., Carmo, H., & Carvalho, F. (2021). Neurotoxicity of psychoactive substances: A mechanistic overview. Current Opinion in Toxicology, 28, 76-83. doi:10.1016/j.cotox.2021.10.002

Paschoal LRP, Rocha S., Zara FJ, Alves Â, Casal G. and Azevedo C. Ultrastructure of two microsporidians Inodosporus sp. And Myospora sp. co-infecting muscles of the Amazon River prawn Macrobrachium amazonicum (Heller, 1862). Nauplius (2021) 29: e2021046 

Reis-Mendes, A.; Dores-Sousa, J.L.; Padrão, A.I.; Duarte-Araújo, M.; Duarte, J.A.; Seabra, V.; Gonçalves-Monteiro, S.; Remião, F.; Carvalho, F.; Sousa, E.; Bastos, M.L.; Costa, V.M. Inflammation as a Possible Trigger for Mitoxantrone-Induced Cardiotoxicity: An In Vivo Study in Adult and Infant Mice. Pharmaceuticals 202114, 510.

Novais, P.; Silva, P.M.A.; Amorim, I.; Bousbaa, H. Second-Generation Antimitotics in Cancer Clinical Trials. Pharmaceutics 202113, 1011.

Henriques AC, Silva PMA, Sarmento B, Bousbaa H. Antagonizing the spindle assembly checkpoint silencing enhances paclitaxel and Navitoclax-mediated apoptosis with distinct mechanistic. Sci Rep. 2021 Feb 18;11(1):4139. doi: 10.1038/s41598-021-83743-7.

Henriques AC, Silva PMA, Sarmento B, Bousbaa H. The Mad2-Binding Protein p31comet as a Potential Target for Human Cancer Therapy. Curr Cancer Drug Targets. 2021;21(5):401-415. doi: 10.2174/1568009621666210129095726.

Fonseca, H.; Bezerra, A.; Coelho, A.; Duarte, J.A. Association between Visceral and Bone Marrow Adipose Tissue and Bone Quality in Sedentary and Physically Active Ovariectomized Wistar Rats. Life 202111, 478.

Esteves M, Silva C, Pereira SS, Morais T, Moreira Â, Costa MM, Monteiro MP, Duarte JA. Regular Voluntary Running Inhibits Androgen-Independent Prostate Cancer Growth in Mice. J Phys Act Health. 2021 Apr 12;18(6):653-659. doi: 10.1123/jpah.2020-0761.

Esteves M, Monteiro MP, Duarte JA. The effects of vascularization on tumor development: A systematic review and meta-analysis of pre-clinical studies. Crit Rev Oncol Hematol. 2021 Mar;159:103245. doi: 10.1016/j.critrevonc.2021.103245.

Esteves M, Monteiro MP, Duarte JA. Role of Regular Physical Exercise in Tumor Vasculature: Favorable Modulator of Tumor Milieu. Int J Sports Med. 2021 May;42(5):389-406. doi: 10.1055/a-1308-3476. 

Durães, F.; Silva, P.M.A.; Novais, P.; Amorim, I.; Gales, L.; Esteves, C.I.C.; Guieu, S.; Bousbaa, H.; Pinto, M.; Sousa, E. Tetracyclic Thioxanthene Derivatives: Studies on Fluorescence and Antitumor Activity. Molecules 202126, 3315.

Araújo, A.M., Carvalho, M., Costa, V.M. et al. In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV). Arch Toxicol 95, 509–527 (2021).

Jácomo, A., & Sanmartín Catalán, C. (2021). El cerebro y la conciencia: una propuesta integradora entre Damásio y Zubiri. Pensamiento. Revista De Investigación E Información Filosófica, 77(Extra 295), 573-585.

Hossain R, Quispe C, Herrera-Bravo J, Islam MS, Sarkar C, Islam MT, Martorell M, Cruz-Martins N, Al-Harrasi A, Al-Rawahi A, Sharifi-Rad J, Ibrayeva M, Daştan SD, Alshehri MM, Calina D, Cho WC. Lasia spinosa Chemical Composition and Therapeutic Potential: A Literature-Based Review. Oxid Med Cell Longev. 2021 Dec 28;2021:1602437. doi: 10.1155/2021/1602437.

De Koninck A, Azevedo A, Cardoso M, Teixeira A, Pérez-Mongiovi D. Buccolingual root dimension of permanent mandibular canines as a complementary estimator of sex: a pilot study. Rev Port Estomatol Med Dent Cir Maxilofac. 2021;62(4):217-222.

Silva, E.M.P.; Barreiros, L.; Fernandes, S.R.; Sá, P.; Ramalho, J.P.P.; Segundo, M.A. Acetonitrile Adducts of Tranexamic Acid as Sensitive Ions for Quantification at Residue Levels in Human Plasma by UHPLC-MS/MS. Pharmaceuticals 202114, 1205.

Nunes M, Silva PMA, Coelho R, Pinto C, Resende A, Bousbaa H, Almeida GM and Ricardo S (2021) Generation of Two Paclitaxel-Resistant High-Grade Serous Carcinoma Cell Lines With Increased Expression of P-Glycoprotein. Front. Oncol. 11:752127. doi: 10.3389/fonc.2021.752127

Novais, P.; Silva, P.M.A.; Moreira, J.; Palmeira, A.; Amorim, I.; Pinto, M.; Cidade, H.; Bousbaa, H. BP-M345, a New Diarylpentanoid with Promising Antimitotic Activity. Molecules 202126, 7139.

Esteves M, Monteiro MP, Duarte JA. The Effects of Physical Exercise on Tumor Vasculature: Systematic Review and Meta-analysis. Int J Sports Med. 2021 Dec;42(14):1237-1249. doi: 10.1055/a-1533-1876.

Dinis-Oliveira RJ. Predatory journals and meetings in forensic sciences: what every expert needs to know about this "parasitic" publishing model. Forensic Sci Res. 2021 Nov 22;6(4):303-309. doi: 10.1080/20961790.2021.1989548.

Bravoa, R.R., Carmo, H., Valente, M.J., Silva, J.P., Carvalho, F., Bastos, M.L, da Silva, D.D. (2021). 4-Fluoromethamphetamine (4-FMA) induces in vitro hepatotoxicity mediated by CYP2E1, CYP2D6, and CYP3A4 metabolism. Toxicology, 2021, 152988,

Almeida-Santos, A.C.; Novais, C.; Peixe, L.; Freitas, A.R. Enterococcus spp. as a Producer and Target of Bacteriocins: A Double-Edged Sword in the Antimicrobial Resistance Crisis Context. Antibiotics 2021, 10, 1215.

Dinis-Oliveira, R.J. The Auto-Brewery Syndrome: A Perfect Metabolic “Storm” with Clinical and Forensic Implications. J. Clin. Med. 2021, 10, 4637.

De Marco, P.; Henriques, A.C.; Azevedo, R.; Sá, S.I.; Cardoso, A.; Fonseca, B.; Barbosa, J.; Leal, S. Gut Microbiome Composition and Metabolic Status Are Differently Affected by Early Exposure to Unhealthy Diets in a Rat Model. Nutrients 2021, 13, 3236.

Pérez-Pereira, A.; Maia, A.; Gonçalves, V.; Ribeiro, C.; Tiritan, M.E. Enantioselective Monitoring of Biodegradation of Ketamine and Its Metabolite Norketamine by Liquid Chromatography. Chemosensors 2021, 9, 242.

Langa I, Tiritan ME, Silva D, Ribeiro C. Gas Chromatography Multiresidue Method for Enantiomeric Fraction Determination of Psychoactive Substances in Effluents and River Surface Waters. Chemosensors. 2021; 9(8):224.

Moreira-Pais, A., Ferreira, R., Oliveira, P.A., Duarte, J.A. Sarcopenia versus cancer cachexia: the muscle wasting continuum in healthy and diseased aging. Biogerontology (2021).

Santo, E., Pinho, T., Teixeira, A., Pérez-Mongiovi, D. (2021). Use of intraoral three-dimensional images for the identification of dental morphological traits related to ancestry estimation. Journal of Forensic Science and Medicine. Vol 7(2):70-73. DOI:10.4103/jfsm.jfsm_21_21

Brandão, S.R.; Reis-Mendes, A.; Domingues, P.; Duarte, J.A.; Bastos, M.L.; Carvalho, F.; Ferreira, R.; Costa, V.M. (2021). Exploring the aging effect of the anticancer drugs doxorubicin and mitoxantrone on cardiac mitochondrial proteome using a murine model. Toxicology. 459 (2021) 152852. doi:

de Sousa Gonçalves, R., de Pinho, F. A., Dinis-Oliveira, R. J., Mendes, M. O., de Andrade, T. S., da Silva Solcà, M., Farias Larangeira, D., Silvestre, R., Barrouin-Melo, S. M. (2021). Nutritional adjuvants with antioxidant properties in the treatment of canine leishmaniasis. Veterinary Parasitology, 298, 109526. doi:

Dinis-Oliveira RJ & Vieira ND. (2021). Acute Liver Failure Requiring Transplantation: A possible link to ulipristal acetate treatment? Basic Clin Pharmacol Toxicol. 2021 Jun 29. doi: 10.1111/bcpt.13631


Carraro, M.L., Marques, S., Silva, A.S., Freitas, B., Silva, P.M.A., Pedrosa, J., De Marco, P., Bousbaa, H., Fernandes, C., Tiritan, M.E., Silva, A.M.S., Pinto, M.M.M. (2020). Synthesis of New Chiral Derivatives of Xanthones with Enantioselective Effect on Tumor Cell Growth and DNA Crosslinking. ChemistrySelect 5 2020, , 10285 – 10291.

Silva TJ, Casal G, Soares EC, Rocha S, Santos EL, Oliveira E, Azevedo C. (2020). Ultrastructure of intracytoplasmic Rickettsia-like infection of the gills of the teleost Archosargus probatocephalus (Sparidae) in northeastern Brazil. Rev Bras Parasitol Vet. 2020 Sep 28;29(3):e010020. doi: 10.1590/S1984-29612020067.

Ribeiro C, Gonçalves R, Tiritan ME. (2020). Separation of Enantiomers Using Gas Chromatography: Application in Forensic Toxicology, Food and Environmental Analysis. Crit Rev Anal Chem. 2020 Jun 18:1-25. doi: 10.1080/10408347.2020.1777522.

Valente-Aguiar MS, Falcão AC, Magalhães T, Dinis-Oliveira RJ. (2020). Cadaveric ichthyofauna of the Madeira River in the Amazon basin: the myth of man-eating piranhas. Forensic Sci Med Pathol. 2020 Jun;16(2):345-351. doi: 10.1007/s12024-020-00221-8.

Rocha S, Rangel LF, Casal G, Azevedo C, Rodrigues P, Santos MJ. (2020). Involvement of sphaeractinomyxon in the life cycle of mugiliform-infecting Myxobolus (Cnidaria, Myxosporea) reveals high functionality of actinospore morphotype in promoting transmission. Parasitology. 2020 Oct;147(12):1320-1329. doi: 10.1017/S0031182020001043

Hine PM, Morris DJ, Azevedo C, Feist SW, Casal G. (2020). Haplosporosomes, sporoplasmosomes and their putative taxonomic relationships in rhizarians and myxozoans. Parasitology. 2020 Sep 18:1-44. doi: 10.1017/S0031182020001717.

Barbosa J, Faria J, Garcez F, Leal S, Afonso LP, Nascimento AV, Moreira R, Queirós O, Carvalho F, Dinis-Oliveira RJ. (2020). Repeated Administration of Clinical Doses of Tramadol and Tapentadol Causes Hepato- and Nephrotoxic Effects in Wistar Rats. Pharmaceuticals (Basel). 2020 Jul 10;13(7):149. doi: 10.3390/ph13070149.

Rescorla LA, Ivanova MY, Achenbach TM, Almeida V, Anafarta-Sendag M, Bite I, Caldas JC, Capps JW, Chen YC, Colombo P, da Silva Oliveira M, Dobrean A, Erol N, Frigerio A, Funabiki Y, Gedutienė R, Guðmundsson HS, Heo MQ, Kim YA, Lee TS, Leite M, Liu J, Markovic J, Misiec M, Müller M, Oh KJ, Portillo-Reyes V, Retz W, Sebre SB, Shi S, Sigurðardóttir SH, Šimulionienė R, Sokoli E, Milijasevic D, Zasępa E. (2020). Older adult psychopathology: international comparisons of self-reports, collateral reports, and cross-informant agreement. Int Psychogeriatr. 2020 Sep 4:1-12. doi: 10.1017/S1041610220001532.

Tiritan ME, Pinto M, Fernandes C. (2020). Enantioselective Synthesis, Enantiomeric Separations and Chiral Recognition. Molecules. 2020 Apr 8;25(7):1713. doi: 10.3390/molecules25071713.

Pinto MMM, Fernandes C, Tiritan ME. (2020). Chiral Separations in Preparative Scale: A Medicinal Chemistry Point of View. Molecules. 2020 Apr 21;25(8):1931. doi: 10.3390/molecules25081931.

Pinto JFFTO, Dores AAMDR, Geraldo APA, Peixoto BMRTB, Barbosa MFDS. (2020). Sensory Stimulation Programs in Dementia: a Systematic Review of Methods and Effectiveness. Expert Rev Neurother. 2020 Sep 17. doi: 10.1080/14737175.2020.1825942.

Andrade JC, Almeida D, Domingos M, Seabra CL, Machado D, Freitas AC, Gomes AM. (2020). Commensal Obligate Anaerobic Bacteria and Health: Production, Storage, and Delivery Strategies. Front Bioeng Biotechnol. 2020 Jun 5;8:550. doi: 10.3389/fbioe.2020.00550.

Zacca R, Azevedo R, Chainok P, Vilas-Boas JP, Castro FAS, Pyne DB, Fernandes RJ. (2020). Monitoring Age-Group Swimmers Over a Training Macrocycle: Energetics, Technique, and Anthropometrics. J Strength Cond Res. 2020 Mar;34(3):818-827. doi: 10.1519/JSC.0000000000002762.

Phyo YZ, Teixeira J, Tiritan ME, Cravo S, Palmeira A, Gales L, Silva AMS, Pinto MMM, Kijjoa A, Fernandes C. (2020). New chiral stationary phases for liquid chromatography based on small molecules: Development, enantioresolution evaluation and chiral recognition mechanisms. Chirality. 2020 Jan;32(1):81-97.

Maia AS, Paíga P, Delerue-Matos C, Castro PML, Tiritan ME. (2020). Quantification of fluoroquinolones in wastewaters by liquid chromatography-tandem mass spectrometry. Environ Pollut. 2020 Apr;259:113927. doi: 10.1016/j.envpol.2020.113927.

Machado D, Almeida D, Seabra CL, Andrade JC, Gomes AM, Freitas AC. (2020). Uncovering Akkermansia muciniphila resilience or susceptibility to different temperatures, atmospheres and gastrointestinal conditions. Anaerobe. 2020 Feb;61:102135. doi: 10.1016/j.anaerobe.2019.102135.

Dinis-Oliveira RJ, Magalhães T. (2020). Abuse of Licit and Illicit Psychoactive Substances in the Workplace: Medical, Toxicological, and Forensic Aspects. J Clin Med. 2020 Mar 12;9(3):770. doi: 10.3390/jcm9030770.

Cardoso HFV, Marinho L, Caldas IM, Puentes K, Andrade M, Toso A, Assis S, Magalhães T. (2020). Historical, demographic, curatorial and legal aspects of the BoneMedLeg human skeletal reference collection (Porto, Portugal). Anthropol Anz. 2020 Feb 13;77(1):57-73. doi: 10.1127/anthranz/2019/1023.

Almeida V, Constante D, Leite A, Almeida IF, Rocha JC, Sá R, Teixeira M, Teixeira A. (2020) Influence of disease phase on embitterment and emotional dysregulation in psoriatic patients. Psychol Health Med. 2020 Mar 27:1-18. doi: 10.1080/13548506.2020.1741655.

Monteiro ASM, Carvalho DD, Azevedo R, Vilas-Boas JP, Zacca R, Fernandes R. (2020). Post-swim oxygen consumption: assessment methodologies and kinetics analysis. Physiol Meas. August 2020. doi:10.1088/1361-6579/abb143

Rocha S, Alves A, Antunes C, Fernandes P, Azevedo C, Casal G (2020). Characterisation of sphaeractinomyxon types (Cnidaria: Myxozoa) from marine and freshwater oligochaetes in a Portuguese estuary, with the demise of the endocapsa collective group. Folia Parasitologica. 2020 Feb;67. DOI: 10.14411/fp.2020.002.